One hundred years of chronic obstructive pulmonary disease (COPD)

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One hundred years of chronic obstructive pulmonary disease (COPD).

Chronic obstructive pulmonary disease (COPD) is an increasing health problem and one of the leading causes of morbidity and mortality worldwide, but knowledge about its pathogenesis has increased substantially in recent years. The disease results from interaction between individual risk factors (like enzymatic deficiencies) and environmental exposures to noxious agents, like cigarette smoking, ...

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One hundred years of chronic obstructive pulmonary disease.

Chronic obstructive pulmonary disease (COPD) is a new name for an old malady. The ancients included the disease under the rubric of “catarrh.” In modern times, COPD has come to signify a mixture of chronic bronchitis, asthmatic bronchitis, and emphysema (1, 2). Rarification of the lung in emphysema may progress to form bullae (Figure 1). Cigarette smoking has long been recognized as the predomi...

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ژورنال

عنوان ژورنال: Respiratory Medicine

سال: 2007

ISSN: 0954-6111

DOI: 10.1016/j.rmed.2007.01.015